DIABETES MELLITUS

Expected effects of regenerative medicine on diabetes

Adipose-derived stem cells collected from the patient’s adipose tissue are increased in culture and administered via intravenous drip.

 

When adipose-derived stem cells are administered, thanks to the “homing effects” in which adipose-derived stem cells converge on damaged sites of the body through blood flow, they have the effect of repairing and improving the function of beta cells, which are insulin-producing cells in the islets of Langerhans of the pancreas. The administration also has the effect of repairing blood vessels damaged by diabetes and improving insulin resistance, which weakens the effectiveness of insulin. This treatment can be expected to improve the symptoms of diabetes.

Classification and causes of diabetes

In cases of monozygotic twins, if one of them has type 1 diabetes, there is a 30-70% chance that the other healthy twin will also develop diabetes. It is known that the prevalence of type 2 diabetes among diabetics is 70-90%, and that the incidence rate is 40% if both parents have diabetes.

In cases of type 1 diabetes, environmental factors such as viruses, protein components, and corticosteroids disturb the autoimmune system, destroy pancreatic cells, and cause clinical symptoms. To date, it is known that approximately 20 types of viral infections can cause diabetes.

Diabetes may also develop due to obesity caused by diet and/or lack of exercise, pregnancy, trauma, bruising, surgery, and other stressful situations, as well as adverse reactions to medications for other diseases, such as corticosteroid abuse from arthritis or nerve pain medications.

Diabetes mellitus is also often a complication of hypertension or hyperlipidemia. The above factors can combine to increase insulin resistance in the organs and lead to diabetes, which is characterized by hyperglycemia.

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