Expected Effects of Regenerative Medicine on Osteoarthritis
Adipose-derived stem cells collected from the patient’s adipose tissue are increased in culture and administered into the joint cavity. The administration of adipose-derived stem cells is expected to suppress inflammation due to osteoarthritis thanks to the anti-inflammatory substances secreted by the adipose-derived stem cells. It also regenerates damaged cartilage and improves the friction between joints and bone-on-bone collisions, allowing smooth joint movement and alleviating pain. Improvement of the symptoms of osteoarthritis can therefore be expected.
Joints are able to move smoothly thanks to the cartilage on the surface of bones. When the cartilage is damaged, joint movement is impaired, causing inflammation and pain.
Osteoarthritis is a condition in which cartilage is damaged and joint movement deteriorates, resulting in a variety of symptoms.
Osteoarthritis can cause a variety of symptoms.
Joints are able to move smoothly thanks to the cartilage on the surface of bones. When the cartilage is damaged, joint movement is impaired, causing inflammation and pain. Osteoarthritis is a condition in which cartilage is damaged and joint movement deteriorates, resulting in a variety of symptoms.
Osteoarthritis can cause a variety of symptoms.
In order to improve these symptoms, the damaged site must be repaired. However, because of a lack of blood vessels in the joints, it is difficult for the materials (such as cells) necessary for repair to reach the joint. For this reason, it was believed that once a joint was damaged, it would not repair itself.
In fact, the damage has been treated by secreting synovial membrane-derived stem cells from the synovial membrane that surrounds the joint, into the joint; however, the repair may not be sufficient solely with the patient’s own capabilities. Therefore, it has been considered to be very difficult to fundamentally cure the condition. As a treatment for this difficulty, stem cell treatment has advanced from research to cutting-edge treatment worldwide in recent years.
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